I had a small issue and Live Mesh greatly helped me out.
I was actually remotely logging in and modifying this blog on another machine. However, I wanted to have a backup of the blog.
Since I was connecting remotely to work on the blog, I couldn't use a USB key and just save the blog's VS 2008 solution to it. Thus, I turned to Live Mesh.
Within about 10 minutes I was all setup and within another 10 minutes after that, the entire blog solution was synced with the cloud, and then with my local machine.
I could then open the VS 2008 locally as if I had been working on it locally all along.
You can get started with Microsoft Live Mesh Beta @ http://www.mesh.com
Powerful!